Southern Colorado Commercial Properties For Sale

Southern Colorado offers a unique mix of opportunity and affordability across a diverse and growing region. From the revitalized downtowns of Trinidad and Alamosa to off-grid hospitality ventures near Crestone or Pagosa Springs, this region draws entrepreneurs, developers, and investors seeking room to grow. Listings include everything from historic main street storefronts and industrial flex space to mixed-use buildings, boutique hotels, and development-ready land. Whether you’re launching a creative business in a mountain town, expanding into the San Luis Valley, or investing in long-term regional growth—Southern Colorado delivers untapped potential and breathtaking surroundings.

$1,250,000
16949 CO-69
Walsenburg, CO
3,056 Sqft
$1,500,000
Lots 1-4 HWY 85/87
Walsenburg, CO
$999,900
23054 US-160
Walsenburg, CO
73,000 Sqft
$990,000
27201 County Rd 63.1
Aguilar, CO
9,680 Sqft
$99,500
Lots 24-26 Block 1 La Veta Add
La Veta, CO
$430,000
TBD County Road 71.1
Trinidad, CO
$699,999
601 S US Hwy 85-87
Walsenburg, CO
1,087 Sqft
$1,399,999
601 & 2340 US HWY 85-87 & Bennett Rd
Walsenburg, CO
7,860 Sqft
$400,000
134-138 W 7th St
Walsenburg, CO
8,362 Sqft
$199,900
618-620 Main St
Walsenburg, CO
2,452 Sqft
$6,704,950
36900 El Moro Rd
Trinidad, CO
36,840 Sqft
$325,000
316 Prospect St
Trinidad, CO
2,024 Sqft
$999,999
2340 Bennett Rd
Walsenburg, CO
6,773 Sqft
$189,900
325 Main St
Walsenburg, CO
$204,999
25447 Highway 69
Gardner, CO
1,332 Sqft
$349,900
701 Main St
Walsenburg, CO
2,640 Sqft
$269,000
1503 E Main St
Trinidad, CO
1,200 Sqft
$450,000
15900 County Rd 71.1 Unit 71.1
Trinidad, CO
2,419 Sqft
$775,000
341 N Commercial St
Trinidad, CO
5,300 Sqft
$334,000
164 E Main St
Trinidad, CO
2,390 Sqft
$150,000
155 W Main
Aguilar, CO
2,308 Sqft
$425,000
925 S Main St
Walsenburg, CO
5,185 Sqft
$150,000
512 San Juan Ave
Trinidad, CO
960 Sqft
$280,000
802 Main St
Walsenburg, CO
1,620 Sqft
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